The Centre for Biomedical Research is a collaborative collective of scientists and clinicians who are investigating important biomedical problems. The CBR is a multidisciplinary unit with an emphasis on genetics, molecular biology, and biotechnology. The centre was created to promote interdisciplinary basic and translational biomedical research.
The present day Centre for Biomedical Research began in 1994 as the Centre for Environmental Health. This was established by the molecular biologists Dr. Ben Koop, Dr. David Levin, Dr. Johan de Boer, Dr. Francis Choy and Dr. Barry Glickman who was the first Director.
Medical genetics was the main focus of the Centre at this time. For example, Francis Choy was interested in identifying mutations in genetic diseases. However, a somewhat wider scope was envisioned, hence the name of the Centre for Environmental Health.
The Centre became known for large-scale multidisciplinary approaches to basic science research. Centre members were interested in integrating molecular approaches to the larger picture, such as the physical environment. For example, Barry Glickman, building on his work in DNA mutation and repair, was interested in the environmental factors that interact with DNA. This work was conducted with de Boer and resulted in a method to track DNA damage in a transgenic rat as a model for human DNA in the real world.
During the later 1990s Ben Koop became part of the Human Genome Project, one of two worldwide research networks to announce in June 2000 that they had completed a rough draft of the human genome. Koop’s role was identifying human immune system genes. Koop became the director of the Centre for Environmental Health in 2002.
Meanwhile clinicians from local Victoria-area hospitals also joined the Centre. Membership was also from the BC Cancer Agency and infectious disease experts from UVic’s biochemistry/microbiology department. The research focus was unmistakably medical, and the centre was reborn in 2002 as the Centre for Biomedical Research. In 2004 UVic established a Division of Medical Sciences in conjunction with the UVic-UBC Island Medical Program partnership and there was a natural tendency for further related collaborations.
The breadth and scope of the Centre for Biomedical Research has continued to deepen, expand and strengthen. When the 3rd Director, neuroscientist Dr. E. Paul Zehr began his tenure in 2007 he brought with him a clear vision to firmly establish the Centre as a University-wide multi-faculty enterprise. Additionally, a key focus was to dramatically increase the awareness and profile of the Centre in community stakeholders locally, provincially, and nationally.
At the present time the Centre for Biomedical Research has more than 30 members spanning the Faculties of Science, Social Science, Engineering, and Education, and the Division of Medical Sciences. As such we have members from Biology, Chemistry, Microbiology & Biochemistry, Engineering, Education, Psychology, Mathematics, Medical Sciences, and Exercise Science. Additionally membership includes the Vancouver Island Health Authority, the BC Cancer Agency, and the Victoria Heart Institute Foundation.
How does the nervous system coordinate the arms and legs during walking? Professor Dr. E. Paul Zehr has expanded the focus of neuroscientists studying motor control, leading to new treatments for stroke victims. More
Dr. Chris Upton bridges gap between genetics and computers with the
Dr. Jim Tanaka, a cognitive neuroscientist, is examining whether autistic children can be taught to overcome "face blindness" by engaging a part of their brains, which they use to expertly recognize other objects. More
Dr. Terry Pearson is banking on mass spectrometry to be the next big thing for antibody-based diagnosis. More
Dr. Brad Nelson thinks the time is right for T cell therapy. More
Neuroscientist Dr. Raad Nashmi found a new pathway for nicotine addiction, which also helps explain nicotine’s benefits for those prone to Parkinson’s. More
Whether he is finding a genetic cure or tracking a rare mutation, Dr. Patrick Macleod is a vital link between patients and molecular researchers at the CBR. More
Dr. Ben Koop co-founded the consortium for Genomic Research on All Salmon Project (cGRASP), an international team devoted to understanding salmon from its DNA out: its evolutionary history, its ecology, its health. More
Neuroscientist Dr. Sandra Hundza explores ways to teach people to walk again after a neurotrauma like a stroke or spinal cord injury, based on understanding the neural patterns that control rhythmic movement
The field of signal transduction is fulfilling its early promise of cancer cures. Professor Dr. Perry Howard is looking for signals to kill cancer cells. More
Subheadline for CBR front page flash: Cognitive neuroscientist Dr. Clay Holroyd is rephrasing the symptom of “inability to focus” to “an inability to get the appropriate dopamine reward for focus.” More
If you can’t find the right chemical tool to suit your medical research, you could ask chemist Dr. Fraser Hof to build one. Histone experts eye up Hof’s latest: a synthetic molecule that binds histones, disrupting a gene regulation pathway. More
Forty years after Rachel Carson wrote Silent Spring, Dr. Caren Helbing’s work warns us that we still don’t really know how to test for chemical contaminants in the environment. More
Dr. Barry Glickman helps Health
Dr. Roderick Edwards finds patterns invisible to the naked eye, as he seeks for order in systems as complex as neuronal nets. More
Dr. Johan de Boer describes how a salmon ancestor diverged so quickly into dozens of species thanks to transposons. More
Dr. Brian Christie was one of the first neuroscientists to discover that exercise promotes the generation of new brain cells. In his latest research, he found that exercise can even reverse FAS-related brain damage. More
Dr. Francis Choy's study of inherited diseases has immediate impact on patients. More
Dr. Robert Chow is finding genes that control eye development. More
When Dr. Caroline Cameron is not studying syphilis, she’s catching snot from whales: the strange path from syphilis to marine biology. More
Dr. Robert Burke has seen developmental biology grow up and zoom in. When he helped finish the sea urchin sequence in 2006, the field took another quantum leap forward. More
Dr. Juan Ausio helped figure out the structure and nature of chromatin, which led to the idea of a histone code. More